Pharmacology

Posts on the various pharmacologic therapies in use in the operating room (OR) and intensive care unit (ICU).

  • Chlorhexidine

    Chlorhexidine gluconate (CHG) is an antiseptic solution found in everything from the mouthwash patients receive while on mechanical ventilation to…

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  • Isolyte S

    Isolyte® S is a balanced crystalloid solution created by B. Braun Medical Inc. As a cardiothoracic anesthesiologist and intensivist, it’s…

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  • Enoxaparin

    Enoxaparin (Lovenox) is a low molecular weight heparin (LMWH) routinely administered subcutaneously (SC) for prophylaxis or treatment of deep vein…

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  • Tigecycline

    Tigecycline (Tygacil) is an intravenous glycylcycline antibiotic used to treat a variety of skin/soft tissue infections, complicated intra-abdominal infections, and…

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  • Banana Bag

    The “banana bag” is a colloquial term referring to isotonic crystalloid fluid premixed with thiamine, folic acid, and a multivitamin…

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  • Angiotensin II

    Synthetic human angiotensin II (Giapreza) is an intravenous vasopressor approved in late 2017 for septic or other distributive shock states.…

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  • Doxycycline

    Doxycycline is an oral and intravenous bacteriostatic tetracycline antibiotic which binds to the 30S bacterial ribosomal subunit rendering protein synthesis…

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  • Rifampin

    Rifampin is the most commonly used oral/IV antibiotic among the rifamycins (rifabutin, rifapentine, etc.) Rifampin acts at the level of…

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  • Procainamide

    Procainamide is a type IA antiarrhythmic which prolongs repolarization via sodium channel blockade. This is achieved by slowing conduction through…

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  • Fluconazole

    Fluconazole (Diflucan) is an intravenous and oral antifungal medication that inhibits ergosterol synthesis (an important component of fungal cell membranes).…

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