Pharmacology

Posts on the various pharmacologic therapies in use in the operating room (OR) and intensive care unit (ICU).

  • Photo of Unasyn

    Unasyn

    Unasyn (ampicillin-sulbactam) is an intravenous antibiotic that I most often use for ENT-related infections/prophylaxis but sometimes gynecologic and intraabdominal infections…

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  • Photo of Dopamine In Shock And Kidney Injury

    Dopamine In Shock And Kidney Injury

    In pursuit of evidence-based rationales for my hatred of dopamine, I turned to PubMed and queried the database for “dopamine…

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  • Photo of Midodrine

    Midodrine

    Midodrine (ProAmantine) is an oral and intravenous prodrug. Its active metabolite, desglymidodrine, activates α-1 receptors to produce vaso and venoconstriction…

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  • Photo of Desmopressin (DDAVP)

    Desmopressin (DDAVP)

    Desmopressin (DDAVP, antidiuretic hormone) is a synthetic analog of vasopressin which can be administered IV, IM, subQ, and orally. Compared…

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  • Photo of Nitric Oxide

    Nitric Oxide

    Nitric oxide is a molecule normally made by vascular endothelial cells to decrease vascular resistance in both the systemic and…

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  • Photo of Lefamulin

    Lefamulin

    Lefamulin (Xenleta) is an intravenous and oral antibiotic approved for community acquired bacteria pneumonia (CABP). Similar to antibiotics like clindamycin…

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