• Dexmedetomidine

    Dexmedetomidine

    Dexmedetomidine (Precedex) is a selective intravenous alpha-2 agonist approved for sedation in non-intubated patients in the perioperative setting and short-term sedation for patients on mechanical ventilation. A negative feedback loop is potentiated by binding alpha-2 receptors, decreasing the further release of neurotransmitters from the pre-synaptic neuron. This reduces the sympathetic…

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  • Midazolam

    Midazolam

    Midazolam (Versed) is a relatively short-acting benzodiazepine (“benzo”) which can be administered IV, PO, PR, and even within the neuraxial space to extend the duration/strength of the epidural/spinal block. For these reasons, it’s the most commonly used benzo in anesthesiology. Like all medications in this class, midazolam potentiates the effects…

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