Dexmedetomidine
Dexmedetomidine (Precedex) is a selective intravenous alpha-2 agonist approved for sedation in non-intubated patients in the perioperative setting and short-term sedation for patients on mechanical ventilation. A negative feedback loop is potentiated by binding alpha-2 receptors, decreasing the further release of neurotransmitters from the pre-synaptic neuron. This reduces the sympathetic…


