• Procalcitonin In The Postoperative Patient

    Procalcitonin In The Postoperative Patient

    Procalcitonin is a peptide precursor of calcitonin that becomes detectable in the setting of systemic bacterial infection, driven by cytokines and endotoxin released throughout the body rather than from the thyroid alone. Levels rise over 12-24 hours with bacterial sepsis and fall as the inflammatory signal resolves. This time course,…

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  • Procalcitonin Inflammatory Biomarker

    Procalcitonin Inflammatory Biomarker

    Procalcitonin (PCT) is a 116 amino acid peptide precursor to calcitonin, a hormone involved in calcium homeostasis. PCT increases significantly in the context of proinflammatory bacterial infections but remains low in viral and other inflammatory states. In serum, PCT rises in 2-4 hours and peaks at 4-30 hours, but interestingly…

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