endocrine
Medical
Desmopressin (DDAVP)
Desmopressin (DDAVP, antidiuretic hormone) is a synthetic analog of vasopressin that can be administered IV, IM, subQ, and orally. Compared to vasopressin (generally regarded as a potent vasoconstrictor), DDAVP has less efficacy as a...
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Medical
Octreotide
Sandostatin (octreotide) is a subcutaneous, intramuscular, or intravenous analog to somatostatin - a protein hormone secreted throughout the GI tract - which acts via G-protein coupled receptors to inhibit a myriad of other hormones....
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Medical
50% Dextrose (D50)
50% dextrose solution (D50W) typically comes as a 50 cc pre-filled syringe containing 25 grams of dextrose. As a cardiac anesthesiologist and intensivist, I most commonly administer D50W to treat profound hypoglycemia or in...
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Medical
Hydrocortisone
Hydrocortisone (Solu-Cortef) is a pharmacologic analog of the steroid hormone cortisol (identical structure) that serves as a reference to gauge the relative mineralcorticoid and glucocorticoid potencies of other steroids. This is similar to how...
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PGY-1
Stress Dose Steroids, Weaning, and ACTH Stimulation
Stress dose steroids are used in numerous scenarios including adrenal insufficiency, critical care, and the perioperative period. What's important to understand is that the peak physiologic production of steroid (cortisol) is roughly the equivalent of...
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