nausea
Medical
Promethazine
Promethazine (Phenergan) is an oral, intramuscular (IM), rectal, and intravenous (albeit with caution!) phenothiazine derivative that is both a first-generation antihistamine (H1 receptor antagonism) and a weak typical antipsychotic (D2 receptor antagonism). It also...
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Pharmacology
Bicitra
Sodium citrate/citric acid (Bicitra) is an oral solution I most commonly administered as an anesthesiology resident for aspiration prophylaxis in patients at high risk for aspiration (e.g., obstetric patients prior to C-section) to neutralize...
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Medical
Scopolamine
Scopolamine is a tertiary amine that crosses the blood-brain barrier to exert its anticholinergic effects in the central nervous system (antiemetic, sedative, amnestic) and the periphery. It is available PO, subcutaneously, intravenously, and transdermally...
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Medical
Dexamethasone
Dexamethasone (Decadron) is synthetic adrenocortical steroid roughly 25 times more potent than hydrocortisone and devoid of mineralcorticoid (“sodium retaining”) properties. Therefore, it's primarily used for long acting, anti-inflammatory effects.
In the ICU, I most commonly...
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Medical
Ondansetron
Ondansetron (Zofran) is a common oral and IV medication I use for post-operative nausea/vomiting prophylaxis. It works by antagonizing serotonergic (5-HT3) receptors located in peripheral vagal terminals and in the medulla's area postrema within...
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