Medical
Doxycycline
Doxycycline is an oral and intravenous bacteriostatic tetracycline antibiotic which binds to the 30S bacterial ribosomal subunit rendering protein synthesis ineffective. This class of antibiotics has a broad range encompassing some coverage for MRSA,...
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Medical
Procainamide
Procainamide is a type IA antiarrhythmic which prolongs repolarization via sodium channel blockade. This is achieved by slowing conduction through the ventricular His-Purkinje system thereby widening the QRS complex (and ultimately the QT interval).
As...
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Medical
Reversal With Sugammadex Versus Neostigmine – Postoperative Pulmonary Complications (STRONGER)
Postoperative pulmonary complications (PPCs) come in a wide variety of flavors ranging from atelectasis and pulmonary congestion to respiratory failure and pneumonia. Not only do certain surgeries (upper abdominal and thoracic), age, case duration,...
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Medical
Fluconazole
Fluconazole (Diflucan) is an intravenous and oral antifungal medication that inhibits ergosterol synthesis (an important component of fungal cell membranes). As an intensivist, I most often use this medication to cover Candida albicans infections...
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Medical
Unasyn
Unasyn (ampicillin-sulbactam) is an intravenous antibiotic that I most often use for ENT-related infections/prophylaxis but sometimes gynecologic and intraabdominal infections as well (Zosyn being another common alternative).
Ampicillin, a beta-lactam, is often times degraded by...
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Education
RK.md’s Perioperative And Critical Care Reference Sheet
Ever since finishing my fellowships, I wanted to create a free reference sheet (front and back) containing "high yield" information in the areas of critical care and perioperative medicine. I feel I'm well suited...
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Medical
Dopamine In Shock And Kidney Injury
In pursuit of evidence-based rationales for my hatred of dopamine, I turned to PubMed and queried the database for "dopamine shock" filtered for meta-analyses, randomized controlled trials, and systematic reviews in adult patients since...
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