Celecoxib (Celebrex) is an oral, non-steroidal anti-inflammatory drug (NSAID). This class of medications typically inhibits two major isozymes: COX-1 (responsible for platelet aggregation, kidney perfusion, and gastrointestinal mucosa protection) and COX-2 (produced as a...
Intravenous (IV) acetaminophen (Ofirmev) is a prime example of how multimodal analgesia can be augmented in the perioperative and ICU settings; however, just as with all things, cost drives availability. Literature has emerged trying...
Sufentanil (Sufenta) is the most powerful narcotic (~1000x more potent than morphine) approved for use in humans. In fact, it's so potent and has such a strong affinity for mu-opioid receptors that I routinely...
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