Education
Antibody Structure
With all the discussion surrounding antibody production after receiving a COVID-19 vaccine, let’s talk about the structure of an antibody.
An antibody (immunoglobulin, or Ig) is a protein synthesized by plasma B cells targeting unique...
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Education
How mRNA Vaccines Work – Gene Transcription And Translation
Conventional vaccines typically involve growing a virus in various cell lines, injecting a part of the virus into the host, and relying on the host to mount an immunologic response (ie, create antibodies and...
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Medical
MAC, Cordis, Sheath Introducer – What’s The Difference?
As a cardiothoracic anesthesiologist and intensivist, I routinely place large central lines for resuscitation, vasoactive/inotrope administration, and to facilitate additional monitoring (ie, Swan Ganz catheter). Over the years, I've heard "MAC", "sheath introducer", "Cordis",...
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Sci/Tech
How I Create My Educational Content
I’m in a constant pursuit to learn more about everything! Although cardiothoracic anesthesiology and critical care are my subspecialties, I am interested in all organ systems and their interplay to maintain systemic homeostasis. Consequently, my ideas for...
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Education
RK.md’s Perioperative And Critical Care Reference Sheet
Ever since finishing my fellowships, I wanted to create a free reference sheet (front and back) containing "high yield" information in the areas of critical care and perioperative medicine. I feel I'm well suited...
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Education
Pharmacokinetics
Pharmacokinetic models describe the rate of absorption, distribution, metabolism, and elimination of a particular drug. This can vary significantly based on properties of the drug itself, varying levels of metabolism in the context of...
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Journal
Looking Back At 2019
2019 was the bookend to my formal medical training as I completed my fellowship in cardiothoracic anesthesiology, took my first vacation in over a decade, and started my job as an attending back home...
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Education
Basics Of Mechanical Ventilation
Understanding mechanical ventilation is a fundamental part of intensive care and perioperative medicine. Here's an overview of the basics of mechanical ventilation. Keep in mind that clinically, there are many more things to consider,...
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