hemodynamics

Left Atrial And Ventricular Pressure Throughout The Stages Of Diastole

The left ventricle’s (LV) variously arranged muscle fibers twist and contract during systole, storing potential energy as blood is ejected (imagine wringing water out of a towel). This stored energy is released in diastole:...

WHO Pulmonary Hypertension (PH) Groups

Pulmonary hypertension (PH) is a broad topic encompassing primary and secondary etiologies. Similar to systemic hypertension, PH refers to elevated pressures in the pulmonary vessels. It’s essential to understand how PH is classified and...

MAC, Cordis, Sheath Introducer – What’s The Difference?

As a cardiothoracic anesthesiologist and intensivist, I routinely place large central lines for resuscitation, vasoactive/inotrope administration, and to facilitate additional monitoring (ie, Swan Ganz catheter). Over the years, I've heard "MAC", "sheath introducer", "Cordis",...

Angiotensin II

Synthetic human angiotensin II (Giapreza) is an intravenous vasopressor approved in late 2017 for septic or other distributive shock states. Normally, renin is released by the kidneys in response to decreased perfusion pressure in...

Factors Contributing To Mean Arterial Pressure

In this video, I go over how I approach hypotension/hypertension considering the factors that contribute to mean arterial pressure. Often times, many of these variables affect overall forward flow, so it's important to have...

Dopamine In Shock And Kidney Injury

In pursuit of evidence-based rationales for my hatred of dopamine, I turned to PubMed and queried the database for "dopamine shock" filtered for meta-analyses, randomized controlled trials, and systematic reviews in adult patients since...

RA/CVP Waveform Interpretation

Central venous pressure (CVP) or right atrial pressure (RAP) waveform tracings can often times provide useful insight about a patient’s right ventricle (RV), tricuspid valve (TV), and overall cardiopulmonary status. The waveform morphology is...

Midodrine

Midodrine (ProAmantine) is an oral and intravenous prodrug. Its active metabolite, desglymidodrine, activates α-1 receptors to produce vaso and venoconstriction with resulting increase in blood pressure (BP). This medication has excellent oral bioavailability and...

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